Prof. Giorgio Sartor

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HOME Anthropology Biochemistry of marine organisms Biomolecules Enzymes Membranes Proteins Biochemistry of pollutants Energy Lipids Metabolism SIGNAL TRANSDUCTION Cell Cycle Cytokines Receptors Growth Factor Receptors G-PROTEIN COUPLED RECEPTORS p53 Steroid Hormon Receptors 14-3-3 PROTEINS: Structure, Function, and Regulation A Chemical Biology Approach Demonstrates G Protein beta gamma Subunits Are Sufficient to Mediate Directional Neutrophil Chemotaxis A complex story of receptor signalling A juvenile mouse pheromone inhibits sexual behaviour through the vomeronasal system Activation of phospholipase Cgamma by PI 3-kinase induced PH domain-mediated membrane targeting Conserved activation pathways in G-protein-coupled receptorsConserved activation pathways in G-protein-coupled receptors Coordinating Erk/Mapk Signalling Through Scaffolds and Inhibitors Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go Crystal structure of the b2 adrenergic receptor–Gs protein complex Crystal Structure of the Catalytic Domains of Adenylyl Cyclase in a Complex with Gsa GTPgS Docking and Scoring in Virtual Screening for Drug Discovery: Methods and Applications Emerging paradigms in GPCR allostery: implications for drug discovery Fluorescence/Bioluminescence Resonance Energy Transfer Techniques to Study G-Protein-Coupled Receptor Activation and Signaling From Pheromones to Behavior G Protein–Coupled Receptor Rhodopsin Gi/o Protein-Dependent and -Independent Actions of Pertussis Toxin (PTX) G-Protein-Coupled Receptor Oligomerization and its Potential for Drug Discovery Heterotrimeric G Proteins: Organizers of Transmembrane Signals How opioid drugs bind to receptors It’s all about the structure Membrane Trafficking of G Protein–Coupled Receptors Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1 Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling andmutagenesis approaches to receptor structure and function Nematode and Arthropod Genomes Provide New Insights into the Evolution of Class 2 B1 GPCRs Odorant receptors: a plethora of G-protein coupled receptors PRED-GPCR: GPCR recognition and family classification server Role of helix 8 in G protein-coupled receptors based on structure–function studies on the type 1 angiotensin receptor Snapshot of a signalling complex Snapshot of Activated G Proteins at the Membrane: The Gaq-GRK2-Gbg Complex Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs Structural diversity of G protein coupled receptors and significance for drug discovery Structural insights into G-proteincoupled receptor allostery Structure and Activation of the Visual Pigment Rhodopsin Structural Features of beta2 Adrenergic Receptor: Crystal Structures and Beyond Structure of the adenosine-bound human adenosine A1 receptor–Gi complex Structure of the Class IV Adenylyl Cyclase Reveals a Novel Fold Structure of the delta-opioid receptor bound to naltrindole Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic Structure of the μ-opioid receptor–Gi protein complex The Expanding Roles of Gbg Subunits in G Protein–Coupled Receptor Signaling and Drug Action The G protein-coupled receptor repertoires of human and mouse The G-protein nanomachine The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints The GRAFS classification system of G-protein coupled receptors in comparative perspective The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes The state of GPCR research in 2004 The Very Large G Protein Coupled Receptor (Vlgr1) in Hair Cells Understanding Molecular Recognition by G protein beta-gamma Subunits on the Path to Pharmacological Targeting Archeology BIOCHEMISTRY Biology Chemistry Earth Sciences Medicine Physics Political Sciences Space Sciences Tools for sciences Books
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