Prof. Giorgio Sartor

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HOME Anthropology Biochemistry of marine organisms Biomolecules Enzymes Membranes Proteins Biochemistry of pollutants Energy Lipids Metabolism SIGNAL TRANSDUCTION CELL CYCLE Cytokines Receptors Growth Factors Receptors G-Protein Coupled Receptors p53 Steroid Hormon Receptors Antiproliferation and apoptosis induction of paeonol in HepG2 cells Breaking the cycle: An insight into the role of ERa in eukariotic cell cycle Cdk1 is sufficient to drive the mammalian cell cycle Coordination of Repair, Checkpoint, and Cell Death Responses to DNA Damage Crystal structure of the complex of the cyclinD-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation E2F – at the crossroads of life and death Emerging roles of E2Fs in cancer: an exit from cell cycle control From G0 to S Phase: A View of the Roles Played by the Retinoblastoma (Rb) Family Members in the Rb-E2F Pathway Influence of paeonol on expression of COX-2 and p27 in HT-29 cells Mechanisms of Cyclin-dependent Kinase Regulation: Structures of Cdks, their Cyclin Activators, and Cip and INK4 Inhibitors p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding Pocket proteins and cell cycle control RB and cell cycle progression Retinoblastoma protein: a central processing unit Replication and protection of telomeres RNA-templated DNA repair Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP Structure of the RbC-Terminal Domain Bound to E2F1-DP1: A Mechanism for Phosphorylation-Induced E2F Release The Retinoblastoma Protein and Cell Cycle Control The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases The structure of CDK4/cyclin D3 has implications for models of CDK activation Wnt signaling and stem cell control Archeology BIOCHEMISTRY Biology Chemistry Earth Sciences Medicine Physics Political Sciences Space Sciences Tools for sciences Books
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