Prof. Giorgio Sartor

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HOME Anthropology Biochemistry of marine organisms Biomolecules Enzymes Membranes PROTEINS Biochemistry of pollutants Energy Lipids Metabolism Signal transduction Antifreeze proteins Bioluminescence Heat Shock Proteins Oxygen Transport Proteins p53 PROTEIN STRUCTURE Protein Turnover Prions 14-3-3 PROTEINS: Structure, Function, and Regulation A century-old debate on protein aggregation and neurodegeneration enters the clinic A lysine–cysteine redox switch with an NOS bridge regulates enzyme function A Nanosecond Time-Resolved Fluorescence Study of Recombinant Human Myelin Basic Protein Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species A Nanosecond Time-Resolved Fluorescence Study of Recombinant Human Myelin Basic Protein An Extended Guinier Analysis for Intrinsically Disordered Proteins Architecture of the cytoplasmic face of the nuclear pore Are there pathways for protein folding? Atom-by-atom analysis of global downhill protein folding Atomic-resolution protein structure determination by cryo-EM Autocatalytic cleavage of Clostridium difficile toxin B Basic units of protein structure, folding, and function Causes of trends in amino-acid gain and loss Charge interactions can dominate the dimensions of intrinsically disordered proteins Co-translational protein folding: progress and methods Common features in DNA recognition helices of eukaryotic transcription factors Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy Conformation of Alamethicin in Oriented Phospholipid Bilayers Determined by 15N Solid-State Nuclear Magnetic Resonance Conformational entropy in molecular recognition by proteins Conformational Plasticity of Hepatitis C Virus Core Protein Enables RNA-Induced Formation of Nucleocapsid-like Particles Conformations of amino acids in proteins Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling Crystal structure of the sodium–potassium pump Cyclic Peptides for Protein–Protein Interaction Targets: Applications to Human Disease Dynamic personalities of proteins Enhancement of Time-Resolved Fluorescence Spectroscopy by Overdetermination Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein Evolution of protein fold in the presence of functional constraints Evolutionary bridges to new protein folds: design of C-terminal Cro protein chameleon sequences Expanding the diversity of chemical protein modification allows post-translational mimicry Expanding the Paradigm: Intrinsically Disordered Proteins and Allosteric Regulation Experimental Identification of Downhill Protein Folding Expression of a lipocalin in Pichia pastoris: secretion, purification and binding activity of a recombinant mouse major urinary protein Fold Change in Evolution of Protein Structures Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch Fluorescence Quenching Studies on Enzyme I of the Bacterial Phosphotransferase System Fuzziness in Protein Interactions - A Historical Perspective Geometric criteria of hydrogen bonds in proteins and identification of "bifurcated" hydrogen bonds Hemolithin: a Meteoritic Protein containing Iron and Lithium Interactions of Whey Proteins with Metal Ions Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation Is there a Möbius band in closed protein beta-sheets? Matrix mechanotransduction mediated bythrombospondin-1/integrin/YAP in the vascular remodeling Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions Mechanism of coupled folding and binding of an intrinsically disordered protein Models of transition Modulation of Correlated Segment Fluctuations in IDPs upon Complex Formation as an Allosteric Regulatory Mechanism Molecular Mechanisms for Herpes Simplex Virus Type 1 Pathogenesis in Alzheimer’s Disease Molecular Recognition Features in Zika Virus Proteome Multi-Pronged Interactions Underlie Inhibition of α-Synuclein Aggregation by β-Synuclein Mutations at protein-protein interfaces: Small changes over big surfaces have large impacts on human health Neuroglobin, clues to function and mechanism New Tools and Data for Improving Structures Using All-Atom Contacts On residues in the disallowed region of the Ramachandran map PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer Partner-Mediated Polymorphism of an Intrinsically Disordered Protein Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain condensates Polyproline-II Helix in Proteins: Structure and Function Power generation from ambient humidity using protein nanowires Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis Promiscuous and Selective: How Intrinsically Disordered BH3 Proteins Interact with Their Pro-survival Partner MCL-1 Proteins downhill all the way Proteins hunt and gather Protein function machinery: from basic structural units to modulation of activity Reaching for high-hanging fruit in drug discovery at protein–protein interfaces Role of Tryptophan Residues in Gramicidin Channel Organization and Function Rotational Freedom of Tryptophan Residues in Proteins and Peptides Sequence-to-Conformation Relationships of Disordered Regions Tethered to Folded Domains of Proteins Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex Structures of the nitrogenase complex prepared under catalytic turnover conditions Structure Versus Stochasticity—The Role of Molecular Crowding and Intrinsic Disorder in Membrane Fission Sugar Transport by the Bacterial Phosphotransferase System - THE INTRINSIC FLUORESCENCE OF ENZYME I Synergistic Amyloid Switch Triggered by Early Heterotypic Oligomerization of Intrinsically Disordered α-Synuclein and Tau Targeting Intrinsically Disordered Transcription Factors: Changing the Paradigm The biological impact of mass-spectrometry-based proteomics The DxDxDG Motif for Calcium Binding: Multiple Structural Contexts and Implications for Evolution The molecular mechanism of Hsp90-induced oligomerization of Tau The molecular sociology of the cell The origin of protein interactions and allostery in colocalization The Protein Data Bank (PDB), Its Related Services and Software Tools as Key Components for In Silico Guided Drug Discovery The Quenching-Resolved Fluorescence Spectrum and Its Application to Studies of the Folding/Unfolding of Trypsin Inhibitor from Seedsof the Bitter Gourd The Ramachandran plots of glycine and pre-proline The shape of protein structures to come The structural basis of calcium transport by the calcium pump Theory for protein folding cooperativity: helix-bundles Thermal Stability of Lysozyme Langmuir−Schaefer Films by FTIR Spectroscopy Thermodynamics and Kinetics of Downhill Protein Folding Investigated with a Simple Statistical Mechanical Model Uncoupling the Folding and Binding of an Intrinsically Disordered Protein Understanding protein folding via free-energy surfaces from theory and experiment Utilizing Coarse-Grained Modeling and Monte Carlo Simulations to Evaluate the Conformational Ensemble of Intrinsically Disordered Proteins and Regions Archeology BIOCHEMISTRY Biology Chemistry Earth Sciences Medicine Physics Political Sciences Space Sciences Tools for sciences Books
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