Prof. Giorgio Sartor

HOME Hydroxy and oxydized fatty acids My publications 3-Ketosteroid 9a-hydroxylase enzymes: Rieske non-heme monooxygenases essential for bacterial steroid degradation 9-Hydroxy-10,12-octadecadienoic acid (9-HODE) and 13-hydroxy-9,11-octadecadienoic acid (13-HODE): excellent markers for lipid peroxidation A Study of the Fatty Acid Metabolism of the Yeast Pityrosporum ovale AIG1 and ADTRP are Atypical Integral Membrane Hydrolases that Degrade Bioactive FAHFAs (Supplementary) Biochemical Diversity of 2-Oxoglutarate-Dependent Oxygenases Cellular Fatty Acid Metabolism and Cancer Characteristic Features of Hydroxystearic Acid Monolayers at the Air/Water Interface Circulating hydroxy fatty acids in familial Mediterranean fever Cutin Monomers: Biosynthesis and Plant Defense Dimorphecolic Acid-A Unique Hydroxydienoid Fatty Acid DIRECT EVIDENCE FOR BIOSYNTHETIC RELATIONSHIPS AMONG HYDROCARBONS, SECONDARY ALCOHOLS AND KETONES IN BRASSICA OLERACEA Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects Enzymatic kinetic resolution of hydroxystearic acids: A combined experimental and molecular modelling investigation Epigenetics and cancer treatment Exploring the Hydroxylation-Dehydrogenation Connection: Novel Catalytic Activity of Castor Stearoyl-ACP Delta9 Desaturase Exotic biomodification of fatty acids Fatty acid desaturation: variations on an oxidative theme Fatty acid oxygenase activity of human hair roots Fatty Aldehyde and Fatty Alcohol Metabolism: Review and Importance for Epidermal Structure and Function Five Decades with Polyunsaturated Fatty Acids: Chemical Synthesis, Enzymatic Formation, Lipid Peroxidation and Its Biological Effects Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes HYDROXYLATION OF 9-HYDROXYSTEARATE BY A SOLUBLE CYTOCHROME P-450-DEPENDENT FATTY ACID HYDROXYLASE FROM BACILLUS MEGATERIUM HYDROXYSTEARATES AS INHIBITORS OF PALMITATE HYDROXYLATION CATALYZED BY THE CYTOCHROME P-450 MONOOXYGENASE FROM BACILLUS MEGATERIUM Hydroxystearic Acids and the Biosynthesis of Unsaturated Fatty Acids Identification of Nine Acetylenic Fatty Acids, 9-Hydroxystearic Acid and 9,10.Epoxystearic Acid in the Seed Oil of Jodina rhombifolia Hook et Arn. (Santalaceae) Identification of 9-Hydroxyoctadecadienoic Acid and Other Oxidized Free Fatty Acids as Ligands of the G Protein-coupled Receptor G2A Isoricinoleic Acid in Semecarpus kurzii Seed Oil Lipid Peroxidation and Lipid Antioxidants in Normal and Tumor Cells Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions Lipid Peroxidation: Chemical Mechanism, Biological Implications and Analytical Determination Lipid peroxidation: Mechanisms, inhibition, and biological effects Lipid peroxides induce expression of catalase in cultured vascular cells Lipolysis: pathway under construction Lipoxygenases – Structure and reaction mechanism Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate Mechanism of Selective Inhibition of Human Prostaglandin G/H Synthase-1 and 2 in Intact Cells Mechanisms and Stereochemistry in Fatty Acid Metabolism Metabolic Alterations of Fatty Acids Metabolism of Hydroxy Fatty Acids -VI. Structure of Hydroxy Acids and the Degradation by Escherichia coli K-12 Mixed regiospecificity compromises alkene synthesis by a cytochrome P450 peroxygenase from Methylobacterium populi Novel Fatty Acid Dioxygenases of Human and Plant Pathogenic Fungi Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice Oxylipins: Structurally diverse metabolites from fatty acid oxidation Production of Eicosanoids and Other Oxylipins by Pathogenic Eukaryotic Microbes Production of Hydroxy Fatty Acids by Biocatalysis Prostaglandin-H-synthase (PGHS)-1 and -2 microtiter assays for the testing of herbal drugs and in vitro inhibition of PGHS-isoenzyms by polyunsaturated fatty acids from Platycodi radix Quantitation of hydroxylated byproduct formation in a Saccharomyces cerevisiae Delta9 desaturating system Stereochemical Analysis of Sulfoxides Obtained by Diverted Desaturation STEREOCHEMISTRY IN THE FORMATION OF 9-HYDROXY-10,12-OCTADECADIENOIC ACID AND 13.HYDROXY-9,11-OCTADECADIENOIC ACID FROM LINOLEIC ACID BY FATTY ACID CYCLOOXYGENASE Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation (Supplementary) Stereospecific Conversion of Oleic Acid to 10-Hydroxystearic Acid Stereospecificity of Microbial Hydrations of Oleic Acid to 10-Hydroxystearic Acid Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes Subcellular Localization of Membrane-Bound Aryl-Hydrocarbon Hydroxylase and NAD(P)H-Dependent Reductase Activities in Mouse Liver Synthesis of monohydroxylated fatty acids from linoleic acid by rat aortic smooth muscle cells and tissues: influence on prostacyclin production The Metabolism of Hydroxystearic Acids in Yeast The Stereospecific Conversion of Stearic Acid to Oleic Acid Unraveling the pathway of lipid oxidation in the young pig: Assessment of hepatic β-oxidation and characterization of carnitine palmitoyltransferase I (CPT I) Links More Links Teaching material References
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